Database of Tox Profiles

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Ensure a successful TPD notification with our Tox Database

With over 340 toxicological profiles on common ingredients used in e-liquids and e-cigarettes, our database has been specifically created to assist the vape industry in meeting the TPD notification requirements for the EU and UK authorities.

About the tox profiles

Our profiles are comprehensive and TPD-ready, providing you with the information you need to comply with regulations and market your products with confidence. Each tox profile includes a summary of a literature search, reference (author), heated or non-heated status, and more.

Ensure a successful TPD notification

Our tox profiles have been used over the years in thousands of TPD notifications. We have a 100% success rate!

UK-based toxicologist

All profiles are prepared and maintained by an experienced, UK-based toxicologist.

Each toxicological report includes:

  • Existence of studies that inform about the chemistry and/or toxicity of emissions
  • Existence of any studies relating to the carcinogenicity, mutagenicity or toxicity for reproduction of the ingredient.
  • Existence of in vitro and in vivo assays to evaluate the toxicological effects of the ingredient on the heart, blood vessels or respiratory tract.
  • Existence of an analysis of the possible addictive properties of the ingredient
  • Existence of any other toxicological data

CBD Vapes

In many EU markets CBD vapes are not permitted due to EU Tobacco Products Directive rules. In those markets that allow CBD vapes the tox profile database is required as part of the notification. To support clients making CBD vape submissions we have updated the database to include CBD and CBG.

Recently added to the database

  • Cannabidiol (CAS 13956-29-1 EC No. 689-176-3); CBD
  • Cannabigerol (CAS 25654-31-3 EC No. 875-470-0); CBG
  • Acetol (CAS 116-09-6)
  • (E)-hex-3-enyl butyrate (CAS 53398-84-8)
  • 3-Methylbutyl isobutyrate (CAS 2050-01-3)
  • 3-Methylbutyl valerate (CAS 2050-09-1)
  • 4-Oxovaleric acid (CAS 123-76-2)
  • 6-Isopropyl-3-methylcyclohex-2-enone (CAS 89-81-6)
  • beta-Terpineol (CAS 138-87-4)

Get access to the database

Contact us today to get price and access to the tox database. You will have access to all tox profiles (over 340) including updates for one year from the date of purchase. To retain access for following year, payment of subsequent invoice is required which will be issued on date of renewal. Terms apply.

Cancel anytime

There is no obligation to pay for subsequent years but you will loose access to the updates and new tox profiles.