Add On: Database of Tox Profiles

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Ensure a successful TPD notification with our Tox Database

With over 300 detailed toxicological profiles on common ingredients used in e-liquids and e-cigarettes, our database has been specifically created to assist the vape industry in meeting the TPD notification requirements for the EU and UK authorities.

About the tox profiles

Our profiles are comprehensive and TPD-ready, providing you with the information you need to comply with regulations and market your products with confidence. Each tox profile includes a summary of a literature search, reference (author), heated or non-heated status, and more.

Ensure a successful TPD notification

Our tox profiles have been used over the years in thousands of TPD notifications. We have a 100% success rate!

UK-based toxicologist

All profiles are prepared and maintained by an experienced, UK-based toxicologist.


  • Existence of studies that inform about the chemistry and/or toxicity of emissions.
  • Existence of any studies relating to the carcinogenicity, mutagenicity or toxicity for reproduction of the ingredient.
  • Existence of in vitro and in vivo assays to evaluate the toxicological effects of the ingredient on the heart, blood vessels or respiratory tract
  • Existence of an analysis of the possible addictive properties of the ingredient
  • Existence of any other toxicological data

CBD Vapes

In many EU markets CBD vapes are not permitted due to EU Tobacco Products Directive rules. In those markets that allow CBD vapes the tox profile database is required as part of the notification. To support clients making CBD vape submissions we have updated the database to include CBD and CBG.

Latest ingredients added to the database

  • Cannabidiol (CAS 13956-29-1 EC No. 689-176-3); CBD
  • Cannabigerol (CAS 25654-31-3 EC No. 875-470-0); CBG

Get access to the database

Contact us today to gain access to the database.

Legal Disclaimer

Medic Pro Limited does not provide legal advice. Medic Pro Limited does not accept any liability to any person or company for any financial loss or damage arising from the use of this information or from any failure to give information. By purchasing this digital product you confirm that you accept these terms.