List of cosmetic ingredients to be banned in EU in 2023

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15 March 2023 - 16:15, by , in Cosmetics, News, Comments off

We’ve put together a list of cosmetic ingredients scheduled to be banned in the EU in 2023. Do you have cosmetics that contain any of these ingredients? Cross check your formulations against this list to identify cosmetics to be reformulated. Search the list by chemical name, CAS or EC number.

Draft laws

The list of cosmetic ingredients below are scheduled to be added to Annex II of EU cosmetic regulation. The laws are still in draft (see links below for draft legislation). Cosmetic ingredients listed in Annex II are not permitted for use in cosmetics in the EU. The update does not currently apply to the United Kingdom.


Cosmetic manufactures should aim to sell through products containing a banned ingredient by 1st December 2023. From 1st December 2023 no cosmetic should contain a listed ingredient.

List of cosmetic ingredients banned in EU in 2023

Below is a list of cosmetic ingredients scheduled to be banned in Europe in 2023 (yellow table). A list of cosmetic ingredients banned in 2022 follows this list (blue table).

Substance NameCAS NumberEC Number
Ammonium bromide12124-97-9235-183-8
Dibutyltin bis(2-ethylhexanoate)2781-10-4220-481-2
Dibutyltin di(acetate)1067-33-0213-928-8
Tellurium dioxide7446-07-3231-193-1
Barium diboron tetraoxide13701-59-2237-222-4
2,2-dimethylpropan-1-ol,tribromo derivative; 3-bromo-2,2-bis(bromomethyl)propan-1-ol36483-57-5/
4,4’-sulphonyldiphenol; bisphenol S80-09-1201-250-5
Quinoclamine (ISO); 2-amino-3-chloro-1,4- naphthoquinone2797-51-5220-529-2
Perfluoroheptanoic acid; tridecafluoroheptanoic acid375-85-9206-798-9
methyl N-(isopropoxycarbonyl)-L-valyl- (3RS)-3-(4-chlorophenyl)-β-alaninate; valifenalate283159-90-0608-192-3
6-[C12-18-alkyl-(branched, unsaturated)-2,5- dioxopyrrolidin-1-yl]hexanoic acid, sodium and tris(2-hydroxyethyl)ammonium salts701-271-4
Fluopicolide (ISO); 2,6-dichloro-N-[3-chloro- 5-(trifluoromethyl)-2- pyridylmethyl]benzamide607-285-6239110-15-7
N-(2-nitrophenyl)phosphoric triamide874819-71-3477-690-9
N-(5-chloro-2-isopropylbenzyl)-N– cyclopropyl-3-(difluoromethyl)-5-fluoro-1- methyl-1H-pyrazole-4-carboxamide; isoflucypram1255734-28-1811-438-4
Reaction mass of 3-(difluoromethyl)-1-methyl- N-[(1RS,4SR,9RS)-1,2,3,4-tetrahydro-9-
isopropyl-1,4-methanonaphthalen-5- yl]pyrazole-4-carboxamide and 3- (difluoromethyl)-1-methyl-N-[(1RS,4SR,9SR)- 1,2,3,4-tetrahydro-9-isopropyl-1,4- methanonaphthalen-5-yl]pyrazole-4- carboxamide [>78% syn isomers <15% anti isomers relative content]; isopyrazam
Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents]84696-25-3283-644-7
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3- propanediyl diacrylate; 2,2- bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate;15625-89-5239-701-3
Pentapotassium 2,2’,2’’,2’’’,2’’’’-(ethane-1,2- diylnitrilo)pentaacetate7216-95-7404-290-3
carboxymethyliminobis(ethylenenitrilo)tetra(a cetic acid); Pentetic Acid (INCI)
Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)te traacetate; Pentasodium Pentetate (INCI)140-01-2205-391-3
Acetamiprid (ISO); (1E)-N-[(6-chloropyridin- 3-yl)methyl]-N’-cyano-N– methylethanimidamide; (E)-N1-[(6-chloro-3- pyridyl)methyl]-N2-cyano-N1- methylacetamidine135410-20-7/
Pendimethalin (ISO); N-(1-ethylpropyl)-2,6- dinitro-3,4-xylidene40487-42-1254-938-2
Bentazone (ISO); 3-isopropyl-2,1,3- benzothiadiazine-4-one-2,2-dioxide25057-89-0246-585-8’

Other changes

Entry 1024 of Annex II is replaced by the following:

“2-ethylhexanoic acid and its salts with the exception of those specified elsewhere in Annex VI to Regulation (EC) No 1272/2008”

CAS: 149-57-5/-

EC: 205-743-6/-’

Change comes into effect  from 1st December 2023.

What manufacturers need to do and by when

In order to comply with the ban, cosmetic manufactures must cease to sell cosmetics with listed ingredients from 1st December 2023. Offending cosmetics must be removed from sale by this deadline.

Want to learn about cosmetic regulation? Check out cosmetic regulation and testing course


Learn more by reading the draft legislation:

Regulation (EC) No 1223/2009 as regards the use in cosmetic products of certain substances classified as carcinogenic,mutagenic or toxic for reproduction.

List of ingredients to be banned


The EU Cosmetic Regulation No 1272/2008 sets a standard for categorizing substances as carcinogenic, mutagenic, or toxic for reproduction (CMR). The level of evidence of a substance’s CMR properties determines whether it’s classified as category 1A, 1B, or 2.

CMRs prohibited

Regulation (EC) No 1223/2009’s Article 15 prohibits the use of CMR substances categorized as 1A, 1B, or 2 in cosmetic products. However, an exception is made if the conditions outlined in Article 15(1) or 15(2) are met.

CMRs listed in Annex II

To create consistency in implementing the prohibition of CMR substances and ensure legal certainty, all CMR substances should be included in the list of prohibited substances in Annex II to Regulation (EC) No 1223/2009. Additionally, any relevant substances should be removed from the lists of restricted or allowed substances in Annexes III to VI. Any amendments should be made if the conditions outlined in Article 15(1) or 15(2) are met.

Impact on CPSR

Do you have a cosmetic that contains a banned ingredient? Don’t forget you’ll need to update your cosmetic safety assessment. It is likely that a full new CPSR will be required and attract the full CPSR fee.

EU Annex II List of prohibited ingredients

Download the official EU list in excel format here. (Last update 16th March 2023)

Cosmetic ingredients banned in EU in 2022

Here’s a list of ingredients already banned in the EU last year (40 ingredients). No cosmetic on the EU market today should contain any of the listed ingredients.

Substance NameCAS NumberEC Number
(1RS,2SR,5RS)-2-(4-Chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl) cyclopentanol;Ipconazole, (1R,2S,5R)-rel-115850-69-6
(1RS,2SR,5SR)-2-(4-Chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl) cyclopentanol;Ipconazole, (1R,2S,5S)-rel115937-89-8
(RS)-1-{1-Ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate1101132-67-5701-225-3
2-(4-tert-Butylbenzyl) propionaldehyde80-54-6201-289-8
2-Methoxyethyl acrylate3121-61-7221-499-3
3-(difluoromethyl)-1-methyl-N-(3′,4′,5′-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide907204-31-3620-041-3
Azamethiphos (ISO)35575-96-3252-626-0
Bis(α,α-dimethylbenzyl) peroxide80-43-3201-279-3
Desmedipham (ISO)13684-56-5237-198-5
Diisooctyl phthalate27554-26-3248-523-5
Dimethomorph (ISO)110488-70-5404-200-2
Dioctyltin dilaurate3648-18-8222-883-3
Flurochloridone (ISO)61213-25-0262-661-3
Hymexazol (ISO)10004-44-1233-000-6
Imazamox (ISO)114311-32-9601-305-7
imiprothrin (ISO); reaction mass of [2,5-dioxo-3-(prop-2-yn-1-yl)imidazolidin-1-yl]methyl (1R,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate and [2,5-dioxo-3-(prop-2-yn-1-yl)imidazolidin-1-yl]methyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate72963-72-5428-790-6
Ipconazole (ISO)125225-28-7603-038-1
Iprovalicarb (ISO)140923-17-7604-209-3
Mesotrione (ISO)104206-82-8600-533-4
Paclobutrazol (ISO)76738-62-0616-379-6
Pyrithione zinc13463-41-7236-671-3
Silicon carbide, fibrous308076-74-6
Silicon monocarbide409-21-2206-991-8
Stannane, dioctyl-, bis (coco acyloxy) derivs.91648-39-4293-901-5
Thiamethoxam (ISO)153719-23-4428-650-4
Tris(2-methoxyethoxy) vinylsilane1067-53-4213-934-0
Triticonazole (ISO)138182-18-0
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